Hot Keywords
Tumor Microenvironment Exosomes and Extracellular Vesicles Breast Cancer Metastasis Bone Metastasis Metastatic Renal Cell Carcinoma Lymph node metastasis Mesothelioma Hematological Malignancies Thyroid Cancer Liquid Biopsies Early Diagnosis Lung Cancer Brain Tumors Lymphoma Oncolytic Virus Cervical Cancer Cancer Stem Cells

Top
J Cancer Metastasis Treat 2016;2:147-48. 10.20517/2394-4722.2016.23 ©2016 Journal of Cancer Metastasis and Treatment
Open Access Editorial

Introduction to this special issue on brain tumor cell invasion and metastasis: anatomical, biological and clinical considerations

Department of Oncology, University Children’s Hospital Zürich, Steinwiesstrasse 75, CH-8032 Zürich, Switzerland.

Correspondence Address: Prof. Michael A. Grotzer, Department of Oncology, University Children’s Hospital Zürich, Steinwiesstrasse 75, CH-8032 Zürich, Switzerland. E-mail: michael.Grotzer@kispi.uzh.ch

    Views:1231 | Downloads:418 | Cited:0 | Comments:0 | :0

    This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License (http://creativecommons.org/licenses/by-nc-sa/3.0/), which allows others to remix, tweak and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

    It is my privilege to introduce the readers to this special issue entitled “Brain tumor cell invasion and metastasis: anatomical, biological and clinical considerations”. As cancer is a global epidemic which knows no borders, efforts to better understand biology and to control it should know no borders either. This issue contains a mixture of clinical and preclinical scholarly articles that have been written by scientists from America, Europe, and the Middle East. I hope that the fresh insights represented here will be appreciated by neuro-oncologists and brain cancer researchers across the translational spectrum.

    The role of the PI3K/AKT/mTOR pathway in brain tumor metastasis

    Alexandre Arcaro et al. (Switzerland)

    This article is emphasizing the role of PI3K/AKT/MTOR pathway on glioma growth and metastasis with a specific focus on angiogenesis, glioma cell invasion and inflammation.

    Dissecting brain tumor growth and metastasis in vitro and ex vivo

    Martin Baumgartner et al. (Switzerland)

    This article reviews the in vitro and ex vivo techniques used to study growth and dissemination of brain cancer cells including organotypic slice culture methods.

    Tailored nanocarriers and bioconjugates for combating glioblastoma and other brain tumors

    Mohamed I. Nounou et al. (Egypt)

    This article reviews blood brain barrier hampered drug delivery and suggests new CNS therapeutics delivery techniques by using tailored nanocarriers and bioconjugates.

    Interdisciplinary management of central nervous system metastasis and neoplastic meningitis: recent developments and future perspectives

    Ghazaleh Tabatabai et al. (Germany)

    This article reviews advances in our understanding on the molecular mechanisms leading to invasion of tumor cells to the CNS and highlights the challenges and perspectives in the field of interdisciplinary management of CNS metastasis.

    Brain tumor surgery: supplemental intraoperative imaging techniques and future challenges

    Telmo Augusto Barba Belsuzarri et al. (Brazil)

    This article discusses maximum safe brain tumor resection techniques including methods that are designed for a precise demarcation of brain tumors and their infiltration zones.

    Brain infiltration by cancer cells: different roads to the same target?

    Mayra Paolillo et al. (Italy)

    This review illustrates recent findings of genes and cellular mechanisms that have been found to be involved in brain metastasis and describe the different cell types involved.

    Effects of Gas1 on gliomas: a review on current preclinical studies

    Jose Segovia et al. (Mexico)

    This article reviews the potential therapeutic effect of the tumor suppressor Gas1 for treatment of GBM.

    Targeting cerebrospinal fluid for discovery of brain cancer biomarkers

    Tarek Shalaby et al. (Switzerland)

    This review examines potential and limitations of brain tumor biomarkers in the CSF.

    Gemcitabine followed by radiotherapy in treatment of newly diagnosed high-grade gliomas

    Maha El-Naggar et al. (Egypt)

    This prospective single centre phase II study evaluated the efficiency of gemcitabine as radiosensitizer in the treatment of newly diagnosed high-grade glioma patients.

    Financial support and sponsorship

    Nil.

    Conflicts of interest

    There are no conflicts of interest.

    Cite This Article

    OAE Style

    Grotzer MA. Introduction to this special issue on brain tumor cell invasion and metastasis: anatomical, biological and clinical considerations. J Cancer Metastasis Treat 2016;2:147-8. http://dx.doi.org/10.20517/2394-4722.2016.23

    AMA Style

    Grotzer MA. Introduction to this special issue on brain tumor cell invasion and metastasis: anatomical, biological and clinical considerations. Journal of Cancer Metastasis and Treatment. 2016; 2:147-8. http://dx.doi.org/10.20517/2394-4722.2016.23

    Chicago/Turabian Style

    Grotzer, Michael A.. 2016. "Introduction to this special issue on brain tumor cell invasion and metastasis: anatomical, biological and clinical considerations" Journal of Cancer Metastasis and Treatment. 2: 147-8. http://dx.doi.org/10.20517/2394-4722.2016.23

    ACS Style

    Grotzer, MA. Introduction to this special issue on brain tumor cell invasion and metastasis: anatomical, biological and clinical considerations. J. Cancer Metastasis. Treat. 20162, 147-8. http://dx.doi.org/10.20517/2394-4722.2016.23

    Views
    1231
    Downloads
    418
    Citations
     0
    Comments
    0

    0

    Comments

    Comments must be written in English. Spam, offensive content, impersonation, and private information will not be permitted. If any comment is reported and identified as inappropriate content by OAE staff, the comment will be removed without notice. If you have any queries or need any help, please contact us at support@oaepublish.com.

    © 2016-2022 OAE Publishing Inc., except certain content provided by third parties