Cancer remains a leading cause of death, despite the undeniable progress made in the last decades in the diagnosis and therapeutic treatments. Further improvements are only possible if we understand more in depth how cancer develops and metastasizes, and how it produces its damaging effects on the whole organisms, including immune-suppression and cachexia, that eventually lead to patient death. The goal of the International Workshop No-Cancer 2018 “understanding cancer cell biology to improve diagnosis and therapy” held in 28-30 Oct, in Novara (Italy) is precisely to share the foremost updated knowledge on the biology of cancer and the emerging technologies for early detection of cancer cells and the new “chemo-free” therapeutic options.
This is the third international Conference on Cancer organized under the auspices of the Università del Piemonte Orientale and other Academic and Cultural institutions, and ideally follows the two previous ones “Basic to Translational Medicine 2016: focus on Cancer” and No-Cancer 2017 “From Cancerogenesis to Therapy: new paradigms, new opportunities”, held in Novara. As outlined in the title, the main objective of the present workshop No-Cancer 2018 is to discuss the current knowledge in Cancer Cell Biology with the aim of paving the design of more precise and non-invasive methods for early detection of cancer cells and of more effective and personalized therapeutic interventions.
Twelve internationally renowned speakers coming from Belgium, France, Italy, Germany, Spain, Portugal and United States will present their recent research in a two-day scientific marathon. In addition, eight short communications and thirteen flash communications have been selected from the submitted abstracts. The following topics are covered: Oncogenes, onco-suppressors and Non-Coding RNAs in Cancer development; Cancer Cell metabolism and Metabolic cross-talk between cancer cells and stromal cells; Role of diet and of microbiota in cancer progression and response to therapy; Novel non-invasive strategies for early detection of cancer, Genetic alterations predisposing to Cancer; Immune and Drug resistance; cachexia; Clinical trials with novel therapeutics. The invited lectures will focus particularly on ovary cancer, colon cancer, pancreatic cancer, breast cancer, prostate cancer, mesothelioma, and hemato-oncology.
Besides the scientific sessions, participants also can enjoy the social events, which include the city tour, classical music concert and Gala dinner.
Scientific and Social event programs and the Photogallery of the Conference are available at www.isidorolab.com.
This Special Issue of Journal of Cancer Metastasis and Treatment is a collection of the articles and extended abstracts that refer to the lectures presented at the Conference. Commentaries and review articles related to the theme of the Conference are also included.
Ciro Isidoro and Gianluca Gaidano, Guest Editors