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Figure 1. Expression of A2BR on cells in the tumor microenvironment. The tumor microenvironment is very heterogeneous. Besides cancer cells, cancer-associated fibroblasts (CAFs), many different immune cells can infiltrate a tumor, such as tumor infiltrating lymphocytes (TILs), tumor associated macrophages (TAMs), granulocytic and monocytic myeloid-derived suppressor cells (g and mMDSCs) and dentritic cells (DCs). While current studies suggest that in TNBC numbers of TILs positively correlate with good patient outcome, TAMs and MDSC do not