fig4

Peptide nucleic acid-based targeting of microRNAs: possible therapeutic applications for glioblastoma

Figure 4. A. Location of a miR-155-5p binding site within the 3’UTR sequence of Caspase-3 mRNA. B. Effects of cell treatment with 4 µM R8-PNA-a155 and R8-PNA-a155-MUT for 48 h on the miR-155-5p hybridization signal. C. Increase of T98G apoptotic cells after treatment for 48 h with 4 µM R8-PNA-a155. Modified from Milani et al.[109]

Journal of Cancer Metastasis and Treatment
ISSN 2454-2857 (Online) 2394-4722 (Print)

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