fig1

Figure 1. A: Prostate biopsy extensively involved by acinar adenocarcinoma with NE differentiation (5%) at low magnification (hematoxylin and eosin-H&E); B: prostate biopsy with solid area of adenocarcinoma at high magnification (H&E); C: prostate biopsy with diffuse positivity for prostate specific membrane antigen (PSMA, immunohistochemistry); D: prostate biopsy with focal positivity for synaptophysin (immunohistochemistry)