fig3

Figure 3. The effect of leelamine (LLM) treatment on glycolysis-related proteins. Western blots showing the effect of LLM treatment on expression levels of glycolysis-related proteins. The numbers above the bands represent quantitation of the protein level change relative to corresponding ethanol-treated control. The experiment was performed twice, and the results were generally consistent (A). Levels of lactate in the plasma and 22Rv1 xenograft tumors of control and LLM-treated mice (n = 5). The results shown are mean ± SD and statistical significance was determined by Student’s t-test (B).