fig3

Figure 3. Effect of Probasco CM on mouse calvarial defects. (A) Representative microscopic images. Calvaria with defects (red circle showing the initial 1.5 mm round artificial defect before treatment) incubated with only BGJb had less repaired area (white arrow) compared to calvaria treated with Probasco CM. (B) Repaired area was quantified. Data were expressed as mean ± SD. Significant differences were marked with asterisks (***P < 0.001). CM: Conditioned medium.