fig1

Figure 1. Micrographs of MCF-7 breast adenocarcinoma cells cultured as adherent cells (A) and as mammospheres (B), magnification 100×. (C,D) Examples of identification of CSCs with the CD44⁺/CD24^-/low phenotype in the adherent culture and in the culture of mammospheres, respectively; the proportion of CSCs in the culture is shown. Isotype controls were performed (not shown). CSCs: Cancer stem cells.