- Prof. Guo-Feng Xie
- Department of Medicine, Division of Gastroenterology & Hepatology and Program in Oncology, University of Maryland School of Medicine, Baltimore, MD, USA.
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Special Issue Introduction
Colorectal cancer (CRC) is a leading cause of cancer mortality worldwide. Although curative treatment options for advanced disease are still lacking, rapid progress has been made in the last decade in understanding the molecular mechanisms underlying CRC tumorigenesis and progression. Also, robust preventive measures and novel therapies resulted in decreased CRC incidence and improved survival. Reviews in this special issue will allow readers to gain insights into the current states of CRC prevention, detection, treatment and its unique molecular mechanisms.
KeywordsEpidemiology, molecular mechanisms underlying CRC tumorigenesis, invasion and metastasis, role of microRNAs, intestinal microbiota and immune system, animal and enteroid models, tumor markers in CRC, CRC prevention
Submission Deadline31 Jul 2018