- Dr. Rafat A. Siddiqui
- Food Chemistry and Nutrition Science laboratory, Agricultural Research Station, Virginia State University, Petersburg, VA, USA.
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Special Issue Introduction
The term "Nutraceuticals" or "Bioceuticals" is derived from "nutrition" and "pharmaceuticals" for products from food sources to provide health benefits, but not to cure or treat any disease. The nutraceuticals include both phytochemicals and zoochemicals. A more recent trend involves the use of crops and animals for commercially produce bioactive components and now referred to as "farmaceuticals." For simplicity, we define here all these components as "Nutraceuticals," which include modified/unmodified plant- or animal-based food, their extracts alone or in combination, semi-purified and purified phytochemicals or zoochemicals and combination of different bioceuticals. The use of nutraceuticals is growing as these products are often used for preventing chronic diseases, including cancer. These products are often regarded as "safe" and widely believed to cause "no side effects." Usually, no or minimal experimental evidence is available for many such nutraceuticals for their side effects, drug interaction, or efficacy. Cancer patients are often reluctant to use nutraceuticals as these may interfere with their chemotherapy. On the other hand, the use of certain nutraceuticals may improve the efficacy of chemotherapy by acting as adjuvants and cancer patients may benefit from them for improving their conditions. The purpose of this special issue on "Nutraceuticals and Cancer" is to comprehensively review the data from basic and clinical research to discuss the benefits as well as potential adverse effects. We invite authors to submit original research and review articles that address the progress and current understanding of nutraceuticals. The topics are desired focusing on nutraceutical intake, absorption and metabolism; cell signaling and gene expression; and variation in cellular effects due to gene polymorphisms. The overall goal of this special issue is to present readers high-quality scientific pieces of evidence for the use of nutraceuticals that can potentially cause adverse side effects and for the use of nutraceuticals that can improve their anti-cancer treatment.
KeywordsAdjuvants, anti-oxidation, apoptosis, cell cycle, signaling, gene expression, receptors
Submission Deadline30 Nov 2020