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Tumor Microenvironment Exosomes and Extracellular Vesicles Breast Cancer Metastasis Bone Metastasis Metastatic Renal Cell Carcinoma Lymph node metastasis Mesothelioma Hematological Malignancies Thyroid Cancer Liquid Biopsies Early Diagnosis Lung Cancer Brain Tumors Lymphoma Oncolytic Virus Cervical Cancer Cancer Stem Cells

Topic: Breast Cancer Metastasis

A special issue of Journal of Cancer Metastasis and Treatment

ISSN 2454-2857 (Online), ISSN 2394-4722 (Print)

Submission deadline: 30 Aug 2023

Guest Editor(s)

  • Prof. Christos A. Papadimitriou, MD, PhD
    Oncology Unit, Second Department of Surgery, “Aretaieion” University Hospital, National and Kapodistrian University of Athens, Athens, Greece.

    Website | E-mail

  • Prof. Flora Zagouri, MD, PhD
    Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

    Website | E-mail

Special Issue Introduction

Dear Colleagues,

Breast cancer is the most common malignancy and the second leading cause of cancer-related mortality among women worldwide. Metastatic breast cancer is responsible for > 90% of tumor-related deaths, often due to the impairment of vital organ function. Metastatic relapse can occur months to decades after initial diagnosis and treatment. Although the incidence of distant relapses has been shown to decrease and survival times for patients with recurrent disease have improved, 20-30% of patients with early breast cancer still die from metastatic disease. This Special Issue focuses on the multistep process of metastatic recurrence, the phenomenon of tumor dormancy, factors that determine the preference of metastatic lesions to develop at specific anatomic sites, monitoring and evaluating both response to treatment and disease progression, as well as developments in the systemic therapeutic approach of the various breast cancer subtypes with particular emphasis on immunotherapy and molecularly targeted treatments (including CDK4/6 inhibitors), and molecular mechanisms mediating endocrine resistance in hormone receptor-positive breast cancers.

Professor Christos A. Papadimitriou, MD, PhD
Professor Flora Zagouri, MD, PhD

Submission Deadline

30 Aug 2023

Submission Information

For Author Instructions, please refer to
For Online Submission, please login at
Submission Deadline: 30 Aug 2023
Contacts: Grace Wong, Assistant Editor,

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