fig3
From: Tumor heterogeneity and therapy resistance - implications for future treatments of prostate cancer
Figure 3. Prostate cancer stem-like cells (SC) sustain less DNA damage and form more colonies than progenitor cells following etoposide treatment, which correlates with less proliferation. Cancer SC and transit amplifying (TA) cells were selected from primary prostate epithelial cell cultures, treated with 30 μmol/L of etoposide and assessed for (A) colony forming ability, (B) comet assay, (C) γH2AX foci formation and (D) Ki67 expression. Each symbol represents a patient sample
