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    Editorial| Open Access

    Bioconjugate structures vs. composite nanoparticulate carriers: the battle for the future of smart, effective and safe cancer management

    Mohamed Ismail Nounou J Cancer Metastasis Treat 2018;4:29. | doi:10.20517/2394-4722.2018.18
    Published on: 21 Jun 2018  | Viewed:0  | Downloaded:0
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    Review| Open Access

    Immunotherapy in the treatment of colorectal cancer: a new kid on the block

    Andrea Spallanzani , Fabio Gelsomino , Francesco Caputo , Chiara Santini , Kalliopi Andrikou , Giulia Orsi , Margherita Rimini , Stefania Pipitone , Laura Riggi , Camilla Bardasi , Massimiliano Salati , Stefano Cascinu

    In the last few years, the success of anti-PD1 and anti-PDL1 drugs in solid cancers treatment and the advances in molecular biology have provided new potential treatment strategies for patients with metastatic colorectal cancer. Unfortunately, only patients with mismatch repair deficiency seem to... Read more

    This article belongs to the Special Issue Colorectal Cancer Progression and Treatment J Cancer Metastasis Treat 2018;4:28. | doi:10.20517/2394-4722.2018.31
    Published on: 19 Jun 2018  | Viewed:120  | Downloaded:9
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    Commentary| Open Access

    Cancer, circulating tumor cells, and metastasis: could protein-derived peptide fragments impede brain metastases?

    Gerald J. Mizejewski

    The majority of cancer deaths can be attributed to cancer cell metastases that migrate to distant target organs. Brain metastases constitute one of the leading causes of morbidity and mortality among cancer patients, occurring in about 40% of patients with metastatic disease. Thus, there exists... Read more

    J Cancer Metastasis Treat 2018;4:27. | doi:10.20517/2394-4722.2018.20
    Published on: 11 Jun 2018  | Viewed:125  | Downloaded:7
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    Review| Open Access

    Pancreaticoduodenectomy for gastric cancer

    Rie Makuuchi , Tomoyuki Irino , Yutaka Tanizawa , Etsuro Bando , Taiichi Kawamura , Masanori Terashima

    Pancreaticoduodenectomy (PD) is performed to achieve an R0 resection for gastric cancer with pancreatic and/or duodenal invasion. Several retrospective case series have been published, but the sample cohorts in each study were heterogeneous and small. Moreover, the absence of prospective studies... Read more

    This article belongs to the Special Issue Reviews of Gastric Cancer Metastasis and Treatment J Cancer Metastasis Treat 2018;4:26. | doi:10.20517/2394-4722.2018.15
    Published on: 7 Jun 2018  | Viewed:87  | Downloaded:7
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    Original Article| Open Access

    Anti-oxidation properties of leaves, skin, pulp, and seeds extracts from green papaya and their anti-cancer activities in breast cancer cells

    Shrefa A. Hadadi , Haiwen Li , Reza Rafie , Paul Kaseloo , Sarah M. Witiak , Rafat A. Siddiqui

    Aim: Breast cancer is typically detected either during a screening examination or after a woman notices a lump. Breast cancers have different phenotypes depending on the presence/absence of an estrogen receptor (ER) and/or an epidermal growth factor (Her-2) receptor. The objective of the present... Read more

    J Cancer Metastasis Treat 2018;4:25. | doi:10.20517/2394-4722.2018.22
    Published on: 30 May 2018  | Viewed:190  | Downloaded:7
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    Review| Open Access

    Management of metastatic esophagogastric junction adenocarcinoma

    Tasuku Toihata , Yu Imamura , Masayuki Watanabe , Hideo Baba

    The prognosis of metastatic disease of esophagogastric junction adenocarcinoma remains poor, despite using a variety of regimens using cytotoxic agents. Recent understanding of molecular characteristic and tumor microenvironment of this cancer is currently instigating new therapeutic options. In... Read more

    This article belongs to the Special Issue Reviews of Gastric Cancer Metastasis and Treatment J Cancer Metastasis Treat 2018;4:24. | doi:10.20517/2394-4722.2017.82
    Published on: 17 May 2018  | Viewed:299  | Downloaded:20
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    Review| Open Access

    Treatment strategy for metastatic gastric cancer in Japan

    Kojiro Eto , Satoshi Ida , Masayuki Watanabe , Hideo Baba

    Despite recent progress in diagnostic imaging, gastric cancer (GC) is occasionally found at an advanced stage with distant metastasis. As metastatic GC is difficult to cure, the treatment strategy should be considered individually based on the physical and socioeconomic status of patients as well... Read more

    This article belongs to the Special Issue Reviews of Gastric Cancer Metastasis and Treatment J Cancer Metastasis Treat 2018;4:23. | doi:10.20517/2394-4722.2017.73
    Published on: 16 May 2018  | Viewed:304  | Downloaded:23
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    Review| Open Access

    Conversion surgery for stage IV gastric cancer

    Satoshi Ida , Masayuki Watanabe

    Gastric cancer with distant metastases, such as para-aortic lymph node metastases, hepatic metastases, and peritoneal dissemination, is classified as stage IV. In this situation, cancer cells have formed micrometastases throughout the body; therefore, according to the algorithm of the Japanese... Read more

    This article belongs to the Special Issue Reviews of Gastric Cancer Metastasis and Treatment J Cancer Metastasis Treat 2018;4:22. | doi:10.20517/2394-4722.2017.75
    Published on: 16 May 2018  | Viewed:300  | Downloaded:25
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    Original Article| Open Access

    The combined analysis of solid and liquid biopsies provides additional clinical information to improve patient care

    Ana Finzel , Helen Sadik , Gregori Ghitti , Jean-François Laes

    Aim: To investigate if the genetic information provided by sequencing of both solid and liquid biopsies can shed light on tumor heterogeneity, and to understand the clinical usefulness of adding blood profiling to standard tissue analysis in cancer care. Methods: Data from 351 patients with stage... Read more

    J Cancer Metastasis Treat 2018;4:21. | doi:10.20517/2394-4722.2018.10
    Published on: 8 May 2018  | Viewed:761  | Downloaded:46
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    Letter| Open Access

    Hypoxia in prostate cancer

    Peter Vaupel J Cancer Metastasis Treat 2018;4:20. | doi:10.20517/2394-4722.2018.30
    Published on: 7 May 2018  | Viewed:141  | Downloaded:18
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