fig1

Figure 1. Peptide disruption of tumor to stroma communication. The peptide disruption of the tumor-to-stromal cell communication network is displayed together with the connective tissue layers, cell components, and signaling pathways. Note that the top half of the diagram displays the communication network connection indicated by the dashed lines (---) between tumor/stromal cells; while the bottom second half demonstrates the blocked linkage(←--X-→) due to peptide disruption of tumor-to-stoma communication (see text for references and Ref.^[45])